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53 showed that GSH supplementation had beneficial effects on acute clinical signs of inflammatory bowel disease (IBD), whereas some adverse effects were observed in the chronic stages of IBD in this particular disease model
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To explore the underlying mechanism of SP@M in alleviating RA, the synovium and proliferated inflammation tissue around the joints in upper limbs in the saline group and SP@M group were isolated, respectively, for RNA sequencing analysis (Supplementary Fig
Epub 2017 Feb 21 Marathe N, Lohkamp LN, Fehlings MG
These gene products are responsible for a wide range of antioxidant, anti-inflammatory, cytoprotective, and detoxification functions and include catalase, superoxide dismutase (SOD)-3, heme oxygenase-1, glutathione-S-transferases, NAD(P)H-quinone oxidoreductase (NQO1), glutathione peroxidase, and glucuronosyltransferase-1a6 (UGT-1a6) [11]
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